april 2016 –
by retraining the immune system to recognize cancer… and kill it
‘I’m going to spend the rest of my life curing cancer.
cure cancer. prevent cancer. self-perpetuate health.
“Centrally managing the IP is an important break from the way that things are traditionally done,” says Jedd Wolchok, a medical oncologist and the director of the PICI center at Memorial Sloan Kettering. “But even bigger is that the royalties and licensing go into a collective communal fund, if you will, that is redistributed to the individual scientists. So essentially, if the [Parker] experiment works, this becomes a self-perpetuating entity.”
so imagine a self perpetuating entity .. of human energy.. money becomes literally irrelevant.. gone..
It may all sound like more of a logical next step than a revolution—until you come to understand, as Parker has, just how fragmented the cancer-research community has become. Lack of money isn’t the main problem. There’s much in what Parker calls our “dysfunctional human systems” that is getting in the way of anticancer efforts throughout academia, government, and industry: the zeal for secrecy among competitors that prevents the quick sharing of ideas, tools, and platforms; the frenzy of grant applications and publication that keeps brilliant scientists from their real work; the inherent caution, baked into the regulatory system and medical culture itself, that slows the testing of promising ideas in clinical trials.
Immunotherapy differs from more traditional cancer treatments, such as surgery (cutting malignant cells out of the body), chemotherapy and radiation (poisoning the deadly mutants), and even the newer, more precise molecular drugs that attempt to jam the protein signals that tell tumor cells to keep dividing and conquering. Most immunotherapy strategies don’t take aim at cancer cells directly; rather, they rev up the immune system to be more aggressive in its interdiction, or they help it zero in on malignant cells more efficiently, or they silence the “stand down” messages the body sends to T cells, the immune system’s natural-born assassins, so that the cells can continue to seek out and kill their targets. The name given to this last strategy fits the Jason Bourne–like plotline underlying the biology: “checkpoint inhibition.”
Long before his fascination with cancer, Parker was drawn to the study of the immune system by his own profoundly serious food allergies. He takes corticosteroids and carries Benadryl and an EpiPen for emergencies, but he has still ended up in the ER a number of times. Autoimmune disorders run in his family: His mom suffers from Hashimoto’s disease, in which the immune system attacks the thyroid gland.
“We want you to treat her with immunotherapy,” said Parker. Yee had been practicing oncology at the Hutch with this general approach for several years. He was a believer. But there were rules—the Food and Drug Administration had to sign off on each protocol, as did the Hutch’s own Institutional Review Board. “I can only treat melanoma patients right now,” he objected. “I don’t have approval.”
“We’ll send you to an island,” Parker offered—somewhere outside American jurisdiction.
“Sean doesn’t have a traditional motivational cause,” says Benioff. “He’s not doing this to be wealthy or to be known or to be significant. He is not doing this to be loved. He is doing this because he feels it. He feels it deeply inside him, and it’s coming through him in the way that a tree emerges from a seed in the forest. And he can’t actually stop it. It’s something that has taken him over
april 2016 – why Sean thinks we need another social network:
the latest iteration of Parker’s app aspires to be a social network, one based almost entirely on real-time video. The premise of Airtime is the room, a virtual place in which users can share content — be it Instagram photos, YouTube videos, Spotify playlists, Giphy gifs — and enjoy them in real time together. (Here’s a video of the product).
“All the things we could sit here and do in person we ought to be able to do virtually even if we’re separated by great distances.”
For Parker, the current crop of social media options aren’t cutting it. Periscope, Meerkat and Facebook Live, for example, allow users to live stream. But he says people want the option of limiting what they broadcast to smaller, more private audiences.
Sean Parker (born December 3, 1979) is an American entrepreneur and philanthropist who cofounded the file-sharing computer service Napster and served as the first president of the social networking website Facebook. He also cofounded Plaxo, Causes, Airtime, and Brigade, an online platform for civic engagement. He is the founder and chairman of the Parker Foundation, which focuses on life sciences, global public health, and civic engagement. As of November 2015, Parker’s net worth was estimated to be US$ 2.5 billion.
In June 2015, Parker announced a $600 million contribution to launch the Parker Foundation, which focuses on three areas: Life Sciences, Global Public Health and Civic Engagement. It takes an interdisciplinary approach to large-scale challenges, combining insight, capital, science and technology, organization building and public policy.
Since 2005, Parker has been an active donor to cancer research, global public health and civic engagement.
video of Biden –
harness the power of collab and big data – Sean
So much to say about this https://t.co/VtxwLS6g14
Original Tweet: https://twitter.com/Mlsif/status/1043092963184848898
Micah Sifry (@Mlsif) tweeted at 5:44 AM – 21 Sep 2018 :
Plus it’s of no help to #civictech when would-be saviors like Pincus and Sean Parker predictably fail (http://twitter.com/Mlsif/status/1043103547468988418?s=17)
Micah Sifry (@Mlsif) tweeted at 5:57 AM – 21 Sep 2018 :
Sean Parker has burned more than $9 million on Brigade =
90 organizers not hired (http://twitter.com/Mlsif/status/1043106870536351745?s=17)
Micah Sifry (@Mlsif) tweeted at 5:59 AM – 21 Sep 2018 :
And it’s really sad to see ppl like Pincus complain that no one reached out to him from political tech world. That’s not true. Cranky billionaire is not a good look. (http://twitter.com/Mlsif/status/1043107462042316801?s=17)
the social dilemma (doc)